Diazepam is N-demethylated by CYP3A4 and 2C19 to the Energetic metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 towards the active metabolite temazepam. N-desmethyldiazepam and temazepam are equally more metabolized to oxazepam. Temazepam and oxazepam are mostly removed by glucuronidation.Diazepam might generate Bodily dependence